IN VIVO TRANSFECTION KITS: PEG-Liposome, Nanoparticle, Polymer, Lipid, Tissue-targeted

Catalog #5011 LIPID In Vivo Transfection Kit, 1.5 mL (30 injections) $895

Catalog #5021 POLYMER In Vivo Transfection Kit, 1.5 mL (30 injections) $935

Catalog #5031 NANOPARTICLE In Vivo Transfection Kit, 1.5 mL (30 injections) $955

Catalog #5041 PEG-Liposome In Vivo Transfection Kit, 1.5 mL (30 injections) $975

Catalog #5051 PANCREAS-targeted In Vivo Transfection Reagent - 1.5 mL (30 injections) $995

Catalog #5061 LIVER-targeted In Vivo Transfection Reagent - 1.5 mL (30 injections) $995

Catalog #5071 KIDNEY-targeted In Vivo Transfection Reagent - 1.5 mL (30 injections) $995

LIPID-based In Vivo Transfection Kit for Rodents (Mouse, Rat)

  • Cationic lipid liposome-based siRNA and plasmid DNA in vivo delivery reagent
  • Efficient delivery to the liver, pancreas, kidney, and certain tumor types via systemic administration
  • Complete product support information is available at: LIPID In Vivo Transfection Kit

In Vivo Lipid Transfection Kit

Figure 1. Systemic administration (i.v.) of Lipid-based In Vivo reagent conjugated with siRNA targeting Lamin A/C mRNA or non-silencing control siRNA following the recommended protocol. Tissues were collected and RNA isolated 48 hours after first injection. Samples were analyzed by qRT-PCR for Lamin A/C gene expression levels. Ribosomal RNA levels were used to normalize the Lamin A/C data. Data are means ± SD (n=6).

 

Figure 2. Intratumoral administration (i.t.) of Lipid-based In Vivo reagent conjugated with siRNA targeting Lamin A/C mRNA or non-silencing control siRNA following the recommended protocol. Tissues were collected and RNA isolated 48 hours after first injection. Samples were analyzed by qRT-PCR for Lamin A/C gene expression levels. Ribosomal RNA levels were used to normalize the Lamin A/C data. Data are means ± SD (n=6).

 

POLYMER-based In Vivo Transfection Kit for Rodents (Mouse, Rat)

  • Biodegradable polymer-based in vivo reagent
  • Efficient delivery to the lung, liver, kidney, and spleen via systemic administration
  • Complete product support information is available at: POLYMER In Vivo Transfection Kit

In Vivo Polymer Transfection Kit

Figure 3. Systemic administration (i.v.) of Polymer-based In Vivo reagent conjugated with siRNA targeting Lamin A/C mRNA or non-silencing control siRNA following the recommended protocol. Tissues were collected and RNA isolated 48 hours after first injection. Samples were analyzed by qRT-PCR for Lamin A/C gene expression levels. Ribosomal RNA levels were used to normalize the Lamin A/C data. Data are means ± SD (n=6).

Figure 4. Intratumoral administration (i.t.) of Polymer-based In Vivo reagent conjugated with siRNA targeting Lamin A/C mRNA or non-silencing control siRNA following the recommended protocol. Tissues were collected and RNA isolated 48 hours after first injection. Samples were analyzed by qRT-PCR for Lamin A/C gene expression levels. Ribosomal RNA levels were used to normalize the Lamin A/C data. Data are means ± SD (n=6).

 

NANOPARTICLE-based In Vivo Transfection Kit for Rodents (Mouse, Rat)

  • Nanoparticle-based reagent
  • Efficient delivery to the heart, lung, liver, pancreas, kidney, and multiple tumor types via systemic administration
  • Complete product support information is available at: NANOPARTICLE In Vivo Transfection Kit

In Vivo Nanoparticle Transfection Kit

Figure 5. Systemic administration (i.v.) of Nanoparticle-based In Vivo reagent conjugated with siRNA targeting Lamin A/C mRNA or non-silencing control siRNA following the recommended protocol. Tissues were collected and RNA isolated 48 hours after first injection. Samples were analyzed by qRT-PCR for Lamin A/C gene expression levels. Ribosomal RNA levels were used to normalize the Lamin A/C data. Data are means ± SD (n=6).

Figure 6. Intratumoral administration (i.t.) of Nanoparticle-based In Vivo reagent conjugated with siRNA targeting Lamin A/C mRNA or non-silencing control siRNA following the recommended protocol. Tissues were collected and RNA isolated 48 hours after first injection. Samples were analyzed by qRT-PCR for Lamin A/C gene expression levels. Ribosomal RNA levels were used to normalize the Lamin A/C data. Data are means ± SD (n=6).

 

PEG-Liposome In Vivo Transfection Kit for Rodents (Mouse, Rat)

  • PEGylated liposome based reagent
  • Efficient delivery to the spleen, kidney, pancreas, liver, and multiple tumor types via systemic administration
  • Complete product support information is available at: PEG-Liposome In Vivo Transfection Kit

In Vivo PEG-Liposome Transfection Kit

Figure 7. Systemic administration (i.v.) of Liposome-PEG based In Vivo reagent conjugated with siRNA targeting Lamin A/C mRNA or non-silencing control siRNA following the recommended protocol. Tissues were collected and RNA isolated 48 hours after first injection. Samples were analyzed by qRT-PCR for Lamin A/C gene expression levels. Ribosomal RNA levels were used to normalize the Lamin A/C data. Data are means ± SD (n=6).

Figure 8. Intratumoral administration (i.t.) of Liposome-PEG based In Vivo reagent conjugated with siRNA targeting Lamin A/C mRNA or non-silencing control siRNA following the recommended protocol. Tissues were collected and RNA isolated 48 hours after first injection. Samples were analyzed by qRT-PCR for Lamin A/C gene expression levels. Ribosomal RNA levels were used to normalize the Lamin A/C data. Data are means ± SD (n=6).

 

Tissue-targeted In Vivo Transfection Reagents for Rodents (Mouse, Rat):

 

All Altogen® In Vivo Transfection Kits supplied with ready-to-run transfection protocols that eliminate the need for extensive transfection optimization experiments. Read more about in vivo siRNA transfection, research methods and experimental protocols at Altogen's Transfection Resource.

 

Altogen Labs offers contract research studies, including in vivo testing services, xenograft animal models, teratoma formation, tissue targeted siRNA delivery, and in vivo toxicology CRO services.